Search results for "fusion [photon photon]"

showing 10 items of 724 documents

Factors in the global assimilation of collaborative information technologies: an exploratory investigation in five regions

2008

The diffusion of innovation theory is deployed to investigate the global assimilation of collaborative information technologies (CITs). Based on the concepts of IT acquisition and utilization, an assimilation framework is presented to highlight four states (limited, focused, lagging, and pervasive) that capture the assimilation of conferencing and groupware CITs. Data collected from 538 organizations in the United States, Australia, Hong Kong, Norway, and Switzerland are aggregated and analyzed to explore assimilation patterns and the influence of decision-making pattern, functional integration, promotion of collaboration, organization size, and IT function size on the assimilation of CITs.…

Collaborative softwareInformation Systems and ManagementKnowledge managementDiffusion of innovation theory10009 Department of Informaticsbusiness.industrymedia_common.quotation_subjectInformation technologyAssimilation (biology)1803 Management Science and Operations Research000 Computer science knowledge & systemsManagement Science and Operations ResearchComputer Science ApplicationsManagement Information Systems1404 Management Information SystemsPromotion (rank)Geography1706 Computer Science Applications1802 Information Systems and ManagementbusinessLaggingFunction (engineering)media_common
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Cerebral blood flow and cerebral death

1969

At present the diagnosis of cerebral death is based on the absence of manifestations of cerebral function (deep coma, wide pupils, absence of reflexes and spontaneous respiration, isoelectric EEG, etc.) during a variable period of time. However, the absence of vital signs of an organ, even for prolonged periods, is no proof of its death. The death of an organ can only be considered as proved by the demonstration that this organ has remained completely deprived of its blood flow during a period of time that surpasses its ability to survive circulatory arrest. In the case of the brain, the permanent absence of clearance of a radioactive tracer deposed within the brain is considered to demonst…

Comamedicine.medical_specialtymedicine.diagnostic_testbusiness.industryBlood flowOrgan transplantationTransplantationCerebral blood flowAnesthesiamedicineSurgeryNeurology (clinical)medicine.symptomCerebral perfusion pressurebusinessIntracranial pressureCerebral angiographyActa Neurochirurgica
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Further improvements of the water-cooled Pb–17Li blanket

2001

Abstract The water-cooled lithium–lead (WCLL) blanket is based on reduced-activation ferritic–martensitic steel as the structural material, the liquid alloy Pb–17Li as breeder and neutron multiplier, and water at typical PWR conditions as coolant. It was developed for DEMO specifications and shall be tested in ITER. In 1999, a reactor parameter optimization was performed in the EU which yielded improved specifications of what could be an attractive fusion power plant. Compared to DEMO, such a power reactor would be different in lay-out, size and performance, thus requiring to better exploit the potential of the WCLL blanket concept in conjunction with a water-cooled divertor. Several new ap…

Computer scienceMechanical EngineeringDivertorReference designWater cooledNuclear engineeringPower reactorFusion powerLiquid alloyBlanketCoolantNuclear physicsNuclear Energy and EngineeringGeneral Materials ScienceCivil and Structural EngineeringFusion Engineering and Design
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Status of the EU DEMO HCLL breeding blanket design development

2018

International audience; In the framework of the European “HORIZON 2020” innovation and research programme, the EUROfusion Consortium develops a design of a fusion power demonstrator (DEMO). One of the key components in the fusion reactor is the Breeding Blanket (BB) surrounding the plasma, ensuring tritium self-sufficiency, heat removal for conversion into electricity, and neutron shielding. CEA-Saclay, with the support of Wigner-RCP and Centrum výzkumu Řež, is in charge of the development of one of the four BB concepts investigated in Europe for DEMO: the Helium Cooled Lithium Lead (HCLL) BB. The rationales of the HCLL are the use of Eurofer as structural material, eutectic liquid lithium-…

Computer scienceNuclear engineeringBlanketBreeding7. Clean energy01 natural sciences010305 fluids & plasmasTritium breeding ratio0103 physical sciencesGeneral Materials Science010306 general physicsDEMOSettore ING-IND/19 - Impianti NucleariCivil and Structural EngineeringBreeding BlanketHelium gasMechanical EngineeringFusion power[INFO.INFO-MO]Computer Science [cs]/Modeling and SimulationCoolantNuclear Energy and EngineeringElectromagnetic shieldingHCLLBlanketMaterials Science (all)Design evolution
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Insight into Disrupted Spatial Patterns of Human Connectome in Alzheimer’s Disease via Subgraph Mining

2012

Alzheimer’s disease (AD) is the most common cause of age-related dementia, which prominently affects the human connectome. In this paper, the authors focus on the question how they can identify disrupted spatial patterns of the human connectome in AD based on a data mining framework. Using diffusion tractography, the human connectomes for each individual subject were constructed based on two diffusion derived attributes: fiber density and fractional anisotropy, to represent the structural brain connectivity patterns. After frequent subgraph mining, the abnormal score was finally defined to identify disrupted subgraph patterns in patients. Experiments demonstrated that our data-driven approa…

Computer sciencebusiness.industryHuman ConnectomeDiseaseGrey mattermedicine.diseasemedicine.anatomical_structureFractional anisotropySpatial ecologymedicineDementiaDiffusion TractographyArtificial intelligenceA fibersbusinessNeuroscienceInternational Journal of Knowledge Discovery in Bioinformatics
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Discovering Aberrant Patterns of Human Connectome in Alzheimer's Disease via Subgraph Mining

2012

Alzheimer's disease (AD) is the most common cause of age-related dementia, which prominently affects the human connectome. Diffusion weighted imaging (DWI) provides a promising way to explore the organization of white matter fiber tracts in the human brain in a non-invasive way. However, the immense amount of data from millions of voxels of a raw diffusion map prevent an easy way to utilizable knowledge. In this paper, we focus on the question how we can identify disrupted spatial patterns of the human connectome in AD based on a data mining framework. Using diffusion tractography, the human connectomes for each individual subject were constructed based on two diffusion derived attributes: …

Computer sciencebusiness.industryPattern recognitionGraph theoryHuman ConnectomeHuman brainGrey mattercomputer.software_genremedicine.diseaseWhite mattermedicine.anatomical_structureVoxelHuman ConnectomesFractional anisotropymedicineDementiaDiffusion TractographyArtificial intelligencebusinesscomputerDiffusion MRI2012 IEEE 12th International Conference on Data Mining Workshops
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"Islands of Innovation" and "School-Wide Implementations" : Two Patterns of ICT-Based Pedagogical Innovations in Schools

2005

The study reported here is a secondary analysis of data collected in 10 schools as part of Israel’s participation in two international studies: IEA’s SITES Module 2, focusing on innovative pedagogical practices at the classroom level, and the OECD/CERI case studies of ICT and organizational innovation, focusing on ICT-related innovations at the school system level. We identify and analyze two patterns of ICT-based curricular innovations: “islands of innovation” and “school-wide implementations.” In the analysis of both patterns we focus on (a) the levels and domains of innovation reached in schools; (b) the communication agents and school variables affecting the diffusion of the innovation;…

ComputingMilieux_GENERALICT in educationschool-wide implementationisland of innovationComputingMilieux_COMPUTERSANDEDUCATIONdiffusion of innovation
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Study of a water-cooled convective divertor prototype for the DEMO fusion reactor

2000

The plasma facing components of a fusion power reactor have a large impact on the overall plant design, its performance and availability and on the cost of electricity. The present work concerns a study of feasibility for a water-cooled prototype of the convective divertor component of the DEMO fusion reactor. The study has been carried out in two steps. In the first one thermal-hydraulic and neutronic parametric analyses have been performed to find out the prototype optimized configuration. In the second step thermo-mechanical analyses have been carried out on the obtained configuration to investigate the potential and limits of the proposed prototype, with a particular reference to the ma…

ConvectionNeutron transportMaterials scienceHeat fluxCritical heat fluxDivertorNuclear engineeringNUCLEAR FUSION DEMO REACTOR DIVERTOR THERMO-MECHANICSHeat transferMechanical engineeringNuclear fusionFusion powerAIP Conference Proceedings
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Mixed MHD convection and Tritium transport in fusion-relevant configurations

2005

Mixed MHD flow and Tritium transport were computed for a slender poloidal duct, representative of a DEMO HCLL blanket element. 2-D flow and temperature fields were computed in the duct's cross section under the assumption of parallel, fully developed flow, while Tritium concentration C was found by solving a fully 3-D problem with simplifying assumptions at the duct's ends. The spatial distribution of C depended on the intensity and direction of the forced flow. Significant peak factors were obtained if the net flow rate was so low that re-circulation occurred; C maxima were attained near the walls for upward flow, in the core region for downward flow.

ConvectionPhysicsMechanical EngineeringHCLL blanketMechanicsBlanketFusion powerMagnetohydrodynamicVolumetric flow ratePhysics::Fluid DynamicsNuclear physicsNuclear Energy and EngineeringCombined forced and natural convectionFlow conditioningGeneral Materials ScienceDuct (flow)Mixed convectionMagnetohydrodynamicsSettore ING-IND/19 - Impianti NucleariCivil and Structural Engineering
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Mutation Analysis of Core Binding Factor A1 in Patients with Cleidocranial Dysplasia

1999

SummaryCleidocranial dysplasia (CCD) is a dominantly inherited disorder characterized by patent fontanelles, wide cranial sutures, hypoplasia of clavicles, short stature, supernumerary teeth, and other skeletal anomalies. We recently demonstrated that mutations in the transcription factor CBFA1, on chromosome 6p21, are associated with CCD. We have now analyzed the CBFA1 gene in 42 unrelated patients with CCD. In 18 patients, mutations were detected in the coding region of the CBFA1 gene, including 8 frameshift, 2 nonsense, and 9 missense mutations, as well as 2 novel polymorphisms. A cluster of missense mutations at arginine 225 (R225) identifies this residue as crucial for CBFA1 function. …

Core binding factorRecombinant Fusion ProteinsDNA Mutational AnalysisGreen Fluorescent ProteinsMolecular Sequence DataMutation MissenseHuman malformation syndromeCore Binding Factor Alpha 1 SubunitBiologyTransfectionmedicine.disease_causeBone and BonesCleidocranial dysplasiaCell LineFrameshift mutationCBFA1GeneticsmedicineHumansMissense mutationGenetics(clinical)SupernumeraryFrameshift MutationGenetics (clinical)Sequence DeletionGeneticsMutationPolymorphism GeneticCleidocranial DysplasiaCore Binding FactorsArticlesmedicine.diseaseOsteochondrodysplasiaNeoplasm ProteinsRadiographyNuclear localizationLuminescent ProteinsPhenotypeMicroscopy FluorescenceMutation testingTranscription factorHaploinsufficiencyToothTranscription FactorsThe American Journal of Human Genetics
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